Persons with post-thrombotic syndrome who have either a healed ulcer or an open ulcer are candidates for deep venous reconstruction. Post-thrombotic syndrome is a complication of deep venous thrombosis (blood clot in one or more deep veins of the leg). Possible signs and symptoms of post-thrombotic syndrome are pain, edema (accumulation of fluid), hyperpigmentation (increase in skin color), and skin ulceration. The latter symptoms indicate the presence of chronic venous insufficiency. This is a condition in which the valves of the veins do not function adequately, and there is a decrease in the return of blood moving from the legs upward to the trunk of the body.

Besides persons with ulcers, those with pain and/or edema resulting from chronic venous insufficiency may be considered for deep venous reconstruction, according to the decision of the physician and the patient.

In general, deep venous reconstruction is performed on patients whose previous treatment has failed, such as elastic compression or superficial venous surgery.

The typical age of the person considered for deep venous reconstruction is the late 40s.