Natural History of DVT and Reflux

Prepared by Peter Henke, MD.
Corresponding chapter in Handbook of Venous Disorders: Chapter 17

Meissner MH, Manzo RA, Bergelin RO, Markel A, Strandness DE Jr. Deep venous insufficiency: the relationship between lysis and subsequent reflux. J Vasc Surg 1993;18:596-605.

PMID: 8411467
Comment: This study elegantly characterizes the resolution of DVT and venous reflux by duplex ultrasonography.

Meissner MH, Caps MT, Zierler BK, Polissar N, Bergelin RO, Manzo RA, Strandness DE Jr. Determinants of chronic venous disease after acute deep venous thrombosis. J Vasc Surg 1998;28:826-33.

PMID: 9808849
Comment: This study further characterizes how DVT resolve as measured by US, and is now often standard for assessing residual thrombus.